OUR Mission
CUP advances interdisciplinary research and education in proteolysis, bringing together expertise across molecular biology, chemistry, computational science, and biotechnology to understand how proteolytic systems shape life across scales.
Upcoming events
Past events
6 International plant protease conferences
Meet the people behind the CUP
Dr. Simon Stael
Coordinator of CUP
Simon studies protease targets using advanced proteomics, bioimaging, and chemical genetics, including in tissue-wounding systems he has established.
Anna Linusson
CUP PI
Anna integrates computational chemistry, virtual screening, and medicinal chemistry to develop high-precision modulators of proteolysis.
Per-Olof Syrén
CUP PI
Per-Olof combines expertise in organic chemistry, enzyme mechanisms, molecular simulations, and protein engineering to understand and redesign enzymes for biotechnology and green chemistry applications.
Peter Bozhkov
CUP PI
Peter studies proteolysis across kingdoms of life, combining expertise in cell biology, development, and biochemistry. His current research focuses on proteolysis in biomolecular condensates and stress granules.
Elena A. Minina
CUP PI
Alyona combines expertise in cell biology, autophagy, and proteolysis with the development of innovative bioimaging tools for studying cellular and organismal phenotypes.
Cross-continental geography of the CUP collaboration network
Collaborators who produced joined publication(s) with the CUP PIs.
Vanina Alvarez, AR, Protozoan proteases
Alexey Amunts, DE, CryoEM
Daniel Craik, AUS, ligation
John Berges, USA, Phytoplankton proteases
Ilana Bergman-Franck, IL, Proteases
Rudi Beyaert, BE, Inflammation
Kay Bidle, USA, Phytoplankton proteases
Frederic Bornancin, CH, Biomed applications
Magali Casanova, FR, Bacterial pathogenicity
Juan Cazzulo, AR, Protozoan proteases
Nuria Coll, ES, Plant immunity
Daniel Cosgrove, USA, Plant cell wall
Michael Crowley, USA, Comput chem
Steve Decker, USA, HT enzyme engineering
Vishva Dixit, USA, Immunity
Nicolas Fasel, CH, Immunity
Christiane Funk, SE, Bacterial/plant proteases
Patrick Gallois, UK, Plant proteases
Debora Gasperini, DE, Plant wound response
Kris Gevaert, BE, Proteomics
Yet-Ran Chen, TW, Peptidomics
Emilio Gutierrez-Beltran, ES, Biocondensates
Daniel Hofius, SE, Autophagy
Ylva Ivarsson, SE, Protein-protein interaction
Eric Lam, USA, Plant proteases
Christoph Langhammer, SE, Nanofluidics
Roland Ludwig, AT, Redox electrochemistry
Mauricio Machado, BRA, Protozoan proteases
Frank Madeo, AT, Yeast disease models
Emma Master, CA, Enzyme technology
Lynn Megeney, CA, Cell fate signaling
Panagiotis Moschou, SE, Catabolism
Jeremy Mottram, UK, Pathogen biology
Thomas Nyström, SE, Aging
Heinz Osiewacz, DE, Fungal cell death
Christopher Overall, CA, Proteases
Andreas Schaller, DE, Proteases
Vicent Moliner, ES, QM/MM
Inaki Tunon, ES, Enzyme catalysis
Stephan Hailfinger, DE, Cancer
Glenn Hicks, USA, Chemical biology
Mariana Schuster, DE, Proteases
Pitter Huesgen, DE, N-terminomics
Moritz Nowack, BE, Cell death
Celine Masclaux-Daubresse, FR, Proteases
Marina Klemencic, SLO, Proteases
Eugene Koonin, USA, Evolution/bioinformatics
Daniel Krappman, DE, Cancer
Kailash Pandey, IN, Protozoan proteases
Marcin Poreba, PL, Proteases
Jurgen Ruland, DE, Immunity
Guy Salvesen, USA, Proteases
Karin Schumacher, DE, Vacuoles
Yigong Shi, CN, Structural biology
Andrei Smertenko, USA, Plant biology
Jens Staal, BE, Inflammation
Lucia Strader, USA, Biomol condensates
Uwe Bornscheuer, DE, enzyme engineering
Meng-Xiang Sun, CHN, Proteolysis/cell polarity
Margot Thome, CH, Immunity
Hannele Tuominen, SE, Plant biology
Vladimir Uversky, USA, Intrinsic disorder
Johana Misas Villamil, DE, Peptide maturation
Frank Van Breusegem, BE, Plant proteases
Renier van der Hoorn, UK, Plant proteases
Assaf Vardi, IL, Algal proteases
Anton Zavialov, FI, Structural biology
Yasin Dagdas, DE, Autophagy
Glenn Hicks, USA, Chemical biology
Elfriede Dall, AT, Proteases
Ari Sadanandom, UK, Proteases
Jimmy Ytterberg, SE, Protein LC-MS
Patrick Bryant, SE, Structural bioinformatics
CUP 